Top Grossing Comedy Movies in Week 49 of 2006
| Rank | Title | Language | Domestic | Worldwide |
|---|---|---|---|---|
| 1 | Anplagghed al Cinema |  IT | - | $8,604,198 |
| 2 | Van Wilder 2: The Rise of Taj |  EN | $4,300,645 | $6,086,508 |
| 3 | Noodle Boxer |  TH | - | $2,721,507 |
| 4 | The Roses of the Desert | IT | - | $1,932,676 |
| 5 | Pledge This! | EN | - | $1,751,490 |
| 6 | 10 Items or Less | EN | $83,291 | $1,399,222 |
| 7 | Big Nothing | EN | - | $662,081 |
| 8 | Made in Paris |  FR | - | $311,808 |
| 9 | Two Weeks | EN | $47,986 | $47,986 |
| 10 | Among Adults | FR | - | $32,561 |
| 11 | Farce of the Penguins | EN | - | $6,832 |
| 12 | Four Eyed Monsters | EN | $3,135 | $3,135 |
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