Top Grossing Comedy Movies in Week 29 of 2006
| Rank | Title | Language | Domestic | Worldwide |
|---|---|---|---|---|
| 1 | You, Me and Dupree |  EN | $75,628,110 | $130,628,903 |
| 2 | Little Man | EN | $58,645,052 | $104,003,322 |
| 3 | It’s a Boy Girl Thing | EN | $848 | $7,385,679 |
| 4 | Metrosexual |  TH | - | $1,304,391 |
| 5 | The Groomsmen | EN | $128,911 | $818,970 |
| 6 | Vita Smeralda |  IT | - | $707,659 |
| 7 | The Oh in Ohio | EN | $418,689 | $648,183 |
| 8 | The Jungle |  FR | - | $397,113 |
| 9 | Golmaal – Fun Unlimited |  IN | - | $350,948 |
| 10 | Mini's First Time | EN | $49,034 | $156,318 |
| 11 | Grilled | EN | - | $46,663 |
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