Top Grossing Comedy Movies in Week 45 of 2006
| Rank | Title | Language | Domestic | Worldwide |
|---|---|---|---|---|
| 1 | Flushed Away |  EN | $64,665,672 | $178,281,554 |
| 2 | The Santa Clause 3: The Escape Clause | EN | $84,500,122 | $110,768,122 |
| 3 | Volver |  ES | $12,899,867 | $85,605,851 |
| 4 | Franklin and the Turtle Lake Treasure |  FR | - | $4,107,909 |
| 5 | Christmas on July 24th Avenue |  JP | - | $3,866,650 |
| 6 | Job: The Last Grey Cell |  PL | - | $1,042,436 |
| 7 | The Art of Negative Thinking |  NO | - | $826,394 |
| 8 | Scenes of a Sexual Nature | EN | - | $429,931 |
| 9 | The Ro(c)k con Artists |  CS | $5,642 | $5,642 |
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