Driven by a desire for self-improvement, a man discovers a revolutionary product promising a dramatically enhanced version of himself. As he experiences the transformative effects, he uncovers a chilling truth that blurs the lines between ambition and a horrifying consequence.
Does The Substance have end credit scenes?
No!
The Substance does not have end credit scenes. You can leave when the credits roll.
Explore the complete cast of The Substance, including both lead and supporting actors. Learn who plays each character, discover their past roles and achievements, and find out what makes this ensemble cast stand out in the world of film and television.
Margaret Qualley
Sue
Dennis Quaid
Harvey
Vincent Colombe
Man in Suit #2
Oscar Lesage
Troy
Demi Moore
Elisabeth Sparkle
Jordan Ford Silver
Assistant Director - Pump It Up Show
Hugo Diego Garcia
Diego - Boyfriend
Joseph Balderrama
Alexandra Barton
Tiffany Hofstetter
Gore Abrams
Oliver
Robin Greer
Male Nurse
Oscar Salem
2nd Assistant Director - Pump It Up Show
Jiselle Henderkott
Girl Auditioning, Dancer - New Year's Eve Show
Gregory Defleur
Philip Schurer
Tom Morton
Doctor
Matthew Géczy
Olivier Raynal
Akil Wingate
TV Host
Discover where to watch The Substance online, including streaming platforms, rental options, and official sources. Compare reviews, ratings, and in-depth movie information across sites like Metacritic, Rotten Tomatoes, IMDb or TMDb.
See how The Substance is rated across major platforms like IMDb, Metacritic, and TMDb. Compare audience scores and critic reviews to understand where The Substance stands among top-rated movies in its genre.
78
Metascore
7.2
User Score
89%
TOMATOMETER
75%
User Score
7.2 /10
IMDb Rating
71
%
User Score
3.8
From 26K fan ratings
3.88/5
From 8 fan ratings
Challenge your knowledge of The Substance with this fun and interactive movie quiz. Test yourself on key plot points, iconic characters, hidden details, and memorable moments to see how well you really know the film.
What event triggers Elisabeth Sparkle's decision to seek out 'The Substance'?
Discover all the awards and nominations received by The Substance, from Oscars to film festival honors. Learn how The Substance and its cast and crew have been recognized by critics and the industry alike.
Best Motion Picture – Musical or Comedy
Best Picture
Best Original Screenplay
Best Hair and Make-Up
Best Visual Effects
Darryl F. Zanuck Award for Outstanding Producer of Theatrical Motion Pictures
Best Original Screenplay
Best Make Up & Hair
Best Sound
Best Original Screenplay
Best Make Up & Hair
Best Sound
Best Feature
Makeup and Hairstyling
Best Picture
Writing (Original Screenplay)
Read the complete plot summary of The Substance, including all major events, twists, and the full ending explained in detail. Explore key characters, themes, hidden meanings, and everything you need to understand the story from beginning to end.
Elisabeth Sparkle, brilliantly portrayed by Demi Moore, is the dazzling star of a cherished aerobics television show. However, during her fiftieth birthday, she is confronted with a harsh truth: she has been fired from her job. The situation worsens as she watches her massive billboard come crashing down, which spirals into a tragic car accident that lands her in the hospital. Here, fate introduces her to a mysterious flash drive labeled “The Substance,” containing revelations about a ground-breaking serum from an anonymous source, offering the promise of youth and extraordinary beauty. But there’s a sinister twist: “[they] are one.”
After weighing her options, Elisabeth boldly opts for the single-use “Activator”, leading to a shocking transformation. A jagged split appears on her back and from it emerges a younger, captivating alter ego named Sue, played by Margaret Qualley. The enigmatic supplier provides explicit orders for Sue: she must receive daily injections of the “Stabilizer” serum, taken from the unconscious Elisabeth, in order to sustain her youthful appearance.
The two women must navigate a grueling seven-day cycle, alternating their consciousness; one must thrive in the outside world while the other sleeps. Sue quickly steps into Elisabeth’s shoes, reclaiming her role on the aerobics show and enjoying newfound fame and adoration. However, as Elisabeth is forced back into her life, she struggles with profound feelings of inadequacy and self-doubt.
As time goes on, the divide between these two entities grows ominous. Elisabeth, in despair, turns to binge eating and alcohol, while Sue becomes dangerously hooked on the Stabilizer serum, frantic to maintain control over her vibrant existence. This reckless dance only accelerates Elisabeth’s descent into aging.
In a moment of desperation, Elisabeth reaches out to the supplier, who gives her a stark choice: follow the prescribed cycles or eliminate “The Substance” entirely. Conflicted, Elisabeth chooses to sneakily manipulate the situation, using the serum to extend her time as the vivacious Sue, all while hiding her own withering self-worth.
As weeks slip by, Elisabeth’s decline becomes painfully evident. Sue’s ever-growing need for Stabilizer leaves Elisabeth a mere husk of her former self. When an important New Year’s Eve special looms, Sue acquires enough serum to prolong her youthful allure for three months; yet tragedy strikes when she runs out just before the big event, forcing a harrowing return to Elisabeth, who now appears grotesque and warped.
Pushed past her limits, Elisabeth decides to break free from “The Substance” once and for all. A lethal concoction known as “Termination” arrives, promising to eradicate Sue forever. However, at the last moment, Elisabeth, overcome by remorse, revives Sue, shattering their entangled fates.
Enraged at discovering a near-empty vial of Stabilizer—an emblem of Elisabeth’s betrayal—Sue retaliates with brutal vengeance, taking Elisabeth’s life before disappearing into the wild night to seize her moment on stage during the New Year’s Eve celebration.
The aftermath of Elisabeth’s demise crushes Sue, culminating in her physical form’s swift decay. In a frantic bid to preserve her existence, Sue disregards the supplier’s warnings, attempting to manipulate the Activator to create a new version of herself. The result is nightmarish: “Monstro Elisasue,” a monstrous blend of herself and Elisabeth, shocks the live audience with its grotesque visage. Chaos erupts among the horrified spectators, leading to a frenzied decapitation of the creature. Yet, in an unsettling turn, the severed head regenerates rapidly, erupting in a rain of blood. As the audience is enveloped in this horrific spectacle, Monstro Elisasue seizes its chance and escapes into the night, collapsing into a gruesome puddle of its own making.
Emerging from this twisted form, Elisabeth’s face finds its way back to her neglected star on the Hollywood Walk of Fame. Finding solace in its familiarity, she positions herself upon it, merging with the star as she fades away. The next day, the remnants of this macabre scene are ruthlessly scrubbed away by a mechanical floor scrubber, erasing all traces of the bloody extravaganza.
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