
A single diagnosis reshapes a family’s world. The film follows three sisters as they confront the shock of ALS, also called Lou Gehrig’s disease, rallying together to support the affected sibling and navigate the emotional and practical challenges that follow. Their bond and resilience drive this heartfelt true‑story drama.
Does Jenifer have end credit scenes?
No!
Jenifer does not have end credit scenes. You can leave when the credits roll.
Explore the complete cast of Jenifer, including both lead and supporting actors. Learn who plays each character, discover their past roles and achievements, and find out what makes this ensemble cast stand out in the world of film and television.

Edie Falco
Wheelchair Saleswoman

Marisa Tomei
Nina Capelli

Jane Alexander
Marilyn Estess

Fisher Stevens
Dr. Aaron Sanders

Jane Kaczmarek
Valerie Estess

Maddie Corman
Julianne Hoffenberg

Camryn Manheim
Nurse Vandemal

Laura San Giacomo
Jenifer Estess

Jace Alexander

Annabella Sciorra
Meredith Estess

Scott Wolf
Jenifer's Date

Rob Morrow
Dr. Richard Feldman

Vincent Spano
Jack

Julianna Margulies
Jenifer's Psychiatrist

David Eisner
Impatient Passenger

Dave Nichols
Doctor #2

Karen Robinson
Lorna

Cedric Smith
Dr. Richards

Colin Ferguson
Peter

Jason Blicker
Neurologist

Johnie Chase
Bus Driver

Dean Mckenzie
Waiter

Bradley White
Michael

Jim McAleese
Fire Marshal

Christopher Bondy
Jenifer's Father (as Chris Bondy)

Donna Hanover
Herself

Robert Bockstael
Researcher

Reed Rudy
Scotty

Alex Gaistman
Jane (Age 3)

Sarah Bolstridge
Jenifer (Age 12)

Imogen Haworth
Valerie (Age 14)

Danny Mags
Jake (age 6)

Mallory Margel
Meredith (Age 11)

Nadia-Leigh Nascimento
Amy

Willis Robbins
Willis

Jason Sharman
(uncredited)
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