Top Grossing Comedy Movies in March 2001
| Rank | Title | Language | Domestic | Worldwide |
|---|---|---|---|---|
| 1 | Spy Kids |  EN | $112,719,001 | $147,934,180 |
| 2 | The Mexican |  ES | $66,845,033 | $147,845,033 |
| 3 | Exit Wounds | EN | $51,758,599 | $79,958,599 |
| 4 | Heartbreakers | EN | $40,336,607 | $57,756,408 |
| 5 | See Spot Run | EN | $33,357,476 | $43,057,552 |
| 6 | Someone Like You... | EN | $27,343,067 | $38,689,940 |
| 7 | The Brothers | EN | $27,457,409 | $27,958,191 |
| 8 | Tomcats | EN | $13,558,739 | $23,430,766 |
| 9 | Get Over It | EN | $11,576,464 | $19,900,366 |
| 10 | The Dish | EN | $2,552,992 | $16,578,157 |
| 11 | Say It Isn't So | EN | $5,520,393 | $12,320,393 |
| 12 | Girls on Top |  DE | - | $10,038,662 |
| 13 | Kissing Jessica Stein | EN | $7,025,722 | $10,013,424 |
| 14 | Amici ahrarara |  IT | - | $2,430,275 |
| 15 | American Desi | EN | $907,835 | $1,104,408 |
| 16 | When Brendan Met Trudy | EN | $133,376 | $1,069,648 |
| 17 | Un mundo raro | ES | - | $1,049,255 |
| 18 | Blow Dry | EN | $637,769 | $830,286 |
| 19 | Me You Them |  PT | $323,923 | $560,943 |
| 20 | Series 7: The Contenders | EN | $195,065 | $300,086 |
| 21 | Advertising Rules! | DE | - | $32,933 |
| 22 | Visitor Q |  JP | - | $15,678 |
| 23 | Dudes! |  SR | - | $1,833 |
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